. Author manuscript; available in PMC: 2019 Sep 1.

Published in final edited form as: Am J Kidney Dis. 2018 May 18;72(3):390–399. doi: 10.1053/j.ajkd.2018.02.363

Table 3.

Associations of changes in echocardiographic measures from CKD to ESRD and risk of all-cause mortality after ESRD

Variable	Change from CKD to ESRD
Variable	Unadjusted HR (95% CI)	Adjusted¹ HR (95% CI)
Left ventricular mass index, per 1g/m^2.7 increase	1.01 (0.99, 1.02)	1.01 (0.99, 1.03)
Ejection fraction, per 1% decline	1.04 (1.01, 1.05)	1.03 (1.00, 1.06)
Left ventricular geometry
Stable	1.00 (reference)	1.00 (reference)
Worsened	1.14 (0.54, 2.40)	0.63 (0.25, 1.60)
Improved	0.51 (0.20, 1.28)	0.70 (0.27, 1.85)
Diastolic relaxation
Stable	1.00 (reference)	1.00 (reference)
Worsened	1.24 (0.65, 2.34)	1.31 (0.60, 2.86)
Improved	0.96 (0.53, 1.72)	0.95 (0.49, 1.84)
Left atrial volume, per 1 ml/m² increase	1.21 (0.88, 1.67)	0.99 (0.68, 1.45)
Height-adjusted LVESV, per 1-ml/m^2.7 increase	1.05 (1.02, 1.07)	1.04 (1.02, 1.07)
Height-adjusted LVEDV, per 1-ml/m^2.7 increase	1.03 (1.02, 1.05)	1.03 (1.01, 1.05)

Bold=p<0.05

The model is adjusted for age, sex, race, dialysis modality, cardiovascular disease, systolic blood pressure, number of anti-hypertensive med classes, diabetes, current smoker, and BMI. Except for sex, race, and first modality of ESRD, all the variables are from the visit closest to the echocardiographic measures at ESRD.

LVESV, left ventricular end-systolic volume; LVEDV, left ventricular end-diastolic volume