Table IV.
Pathogen Susceptibilities to Common Empiric Antimicrobial Regimens
| Pathogen | Ampicillin/Gentamicin N (%)123 | 3rd generation cephalosporin N (%)12 |
|---|---|---|
| Group B streptococcus | 162/162 (100) | 162/162 (100) |
| E. coli | 124/135 (91.9) | 132/135 (97.8) |
| S. aureus4 | 35/37 (94.6) | 39/43 (90.7) |
| Enterococcus spp.4 | 28/28 (100) | 0/29 (0) |
| Other Gram Negative5 | 10/11 (90.9) | 9/11 (81.8) |
| Klebsiella spp. | 12/14 (85.7) | 12/14 (85.7)V |
| Enterobacter spp. | 10/11 (90.9) | 6/11 (54.5) |
| Group A streptococcus | 11/11 (100) | 11/11 (100) |
| Other Gram Positive6 | 8/8 (100) | 8/8 (100) |
| Salmonella spp. | 6/6 (100) | 6/6 (100) |
| S. pneumoniae | 6/6 (100) | 6/6 (100) |
| L. monocytogenes | 4/4 (100) | 0/4 (0) |
| Total | 416/433 (96.1) | 391/440 (88.9) |
Denominators represent isolates with available susceptibility testing
Some cultures grew >1 organism
Gentamicin has poor cerebrospinal fluid penetration; pathogen considered ampicillin/gentamicin resistant if infant had bacterial meningitis and pathogen was ampicillin-resistant
6 isolates of S. aureus and 1 isolate of Enterococcus spp. had available susceptibility testing to third-generation cephalosporins but not to ampicillin/gentamicin
Includes Citrobacter spp. (3), Pseudomonas aeruginosa (2), Neisseria meningitidis (2), Moraxella spp. (2), Haemophilus influenzae non-typeable (2), Haemophilus parainfluenzae (1), Proteus spp. (1), Serratia spp. (1), Pasteurella spp. (1), Acinetobacter spp. (1)
Includes Streptococcus gallolyticus (4), Streptococcus bovis (4), Paenibacillus spp. (1)