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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: J Pediatr. 2018 May 18;200:210–217.e1. doi: 10.1016/j.jpeds.2018.04.033

Table V.

Distribution of Resistance to Third-Generation Cephalosporins by Demographic, Clinical, and Laboratory Factors

Proportion Resistant to 3rd Generation
Cephalosporins1 N (%)
P-value
Age Group 0.49
≤28 days 27/229 (11.8)
29–60 days 20/206 (9.7)
Gestational Age2 0.58
Preterm (<37w0d) 6/69 (8.7)
Term 38/348 (10.9)
Complex Chronic Condition <0.001
Yes 16/64 (25.0)
No 31/371 (8.4)
Fever 0.11
Yes 35/359 (9.8)
No 12/76 (15.8)
Clinical Appearance 0.83
Ill-Appearing 15/145 (10.3)
Not Ill-Appearing 32/290 (11.0)
Abnormal Urinalysis34 0.52
Yes 17/163 (10.4)
No 19/223 (8.5)
Peripheral WBC <5K or >15K5 0.42
Yes 18/188 (9.6)
No 29/241 (12.0)
1

435 infants had isolates with available susceptibility testing to third-generation cephalosporins

2

18 infants had missing data for gestational age

3

Positive nitrite or leukocyte esterase, or >5 WBC/high-powered field

4

49 infants had no urinalysis results

5

6 infants had no peripheral WBC results

Abbreviations: WBC, white blood cell