. 2017 Apr 25;313(2):E134–E147. doi: 10.1152/ajpendo.00052.2017

Table 3.

Body composition of rats in experiment 3 receiving third-ventricle infusions of leptin

		Leptin
	Saline	0.005 μg	0.01 μg	0.05 μg	0.1 μg
Fat depots
Inguinal, g	4.79 ± 0.35^a	5.00 ± 0.20^a	5.49 ± 0.24^a	2.06 ± 0.62^b	1.04 ± 0.04^b
Epididymal, g	3.03 ± 0.19^a	3.28 ± 0.22^a	3.16 ± 0.18^a	1.35 ± 0.43^b	0.28 ± 0.08^b
Retroperitoneal, g	1.32 ± 0.18^a	1.58 ± 0.12^a	1.53 ± 0.14^a	0.42 ± 0.16^b	0.25 ± 0.03^b
Mesenteric, g	1.26 ± 0.20^a	1.59 ± 0.12^a	1.53 ± 0.14^a	0.42 ± 0.16^b	0.25 ± 0.28^b
Carcass composition
Weight, g	308 ± 7^a	315 ± 5^a	312 ± 5^a	263 ± 14^b	228 ± 6^b
Fat, g	19.1 ± 1.9^a	21.4 ± 0.9^a	22.0 ± 1.2^a	7.7 ± 2.6^b	2.5 ± 0.1^b
Lean, g	275 ± 6^a	279 ± 5^a	277 ± 5^a	246 ± 11^b	217 ± 6^b
Ash, g	13.1 ± 0.8	14.8 ± 1.2	13.1 ± 0.6	10.0 ± 0.7	8.4 ± 0.9
Serum assays
Leptin, ng/ml	2.2 ± 0.4^a	2.2 ± 0.4^a	1.9 ± 0.2^a	0.7 ± 0.2^b	0.3 ± 0.1^b
Glucose, mg/dl	200 ± 7	215 ± 15	198 ± 23	158 ± 14	193 ± 8
Insulin, ng/ml	0.82 ± 0.28	1.69 ± 0.48	1.94 ± 0.26	0.90 ± 0.30	1.41 ± 0.51

Values are means ± SE for groups of 7–9 rats euthanized after 16 days of third-ventricle infusions of different doses of leptin in experiment 3. Values for a specific measure that do not share a common superscripted letter are significantly different at P < 0.05.