Table 3.
Control | ConA + V | ConA + CsA | ConA + PS | ConA + ARC | |
---|---|---|---|---|---|
Portal inflammation | 0 ± 0 | 2.0 ± 0.89## | 1.4 ± 0.48* | 0.5 ± 0.65** | 1.0 ± 0.64** |
Edema | 0.1 ± 0.33 | 2.8 ± 0.89## | 1.4 ± 0.48** | 0.8 ± 0.55** | 0.5 ± 0.58** |
Congestion | 0.3 ± 0.43 | 2.3 ± 0.71## | 1.3 ± 0.43** | 2.4 ± 0.85 | 0.4 ± 0.97** |
Necrosis | 0 ± 0 | 2.5 ± 1.20## | 0.4 ± 0.48** | 0.3 ± 0.44** | 0.3 ± 0.42** |
Total liver injury score | 0.4 ± 0.48 | 9.5 ± 2.20## | 4.38 ± 0.70** | 3.9 ± 1.23** | 2.1 ± 0.54** |
Data are expressed as mean ± SD (n = 8), ##p < 0.01 compared with control; *P < 0.05 compared with model mice treated with vehicle; **P < 0.01 compared with model mice treated with vehicle.