Table 1.
Characteristics of systemic sclerosis (SSc) patients and healthy subjects.
| Characteristics | Diffuse SSc | Controls |
|---|---|---|
| Number of subjects | n = 11 | n = 10 |
| Sex (female/male) | 10/1 | 8/2 |
| Age mean (min–max) | 56.3 (26–72) | 30 (15–45) |
| Biospy site | Forearm fibrotic skin | Forearm normal skin |
| Duration of disease in months mean (min–max) | 51 (3–210) | – |
| Rodnan score mean (min–max) | 17.5 (5–29) | – |
| Autoantibodies | 7 anti-topoisomerase I (Scl70) 3 ANA with no specificities |
– |
| Lung fibrosis | 6 | – |
| Pulmonary arterial hypertension | 2 | – |
| Treatments | ||
| Steroids | 6 | – |
| Methotrexate | 4 | – |
| Rituximab | 2 | – |
| Tocilizumab | 1 | – |
| Azathioprine | 1 | – |
Sex, age at time of biopsy, SSc type, disease duration, biopsy site, treatments, Rodnan score, presence/absence of pulmonary arterial hypertension, and autoantibodies were collected for each patient included in this study and reported in this table.