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. 2016 Oct 26;312(1):F121–F133. doi: 10.1152/ajprenal.00231.2016

Fig. 4.

Fig. 4.

Analysis of mRNA expression levels by quantitative real-time PCR for NLRP3 inflammasome components NLRP3 (A), ASC (B), caspase-1 (C), and IL-1β (D) in obstructed kidneys of mPGES-1 WT and KO mice. NLRP3, Nod-like receptor pyrin domain containing 3; ASC, apoptosis-associated speck-like protein containing a caspase recruitment domain; IL-1β: interleukin-1β. WT-Sham, n = 6; WT-7UUO, n = 7; KO-Sham, n = 6; KO-7UUO, n = 7. *P < 0.05 compared with Sham groups. #P < 0.05 compared with WT-7UUO. §P < 0.05 compared with WT-Sham.