Fig. 10.

Insulin receptor (IR) changes its distribution after lovastatin treatment followed by 70% hepatectomy. Immunohistochemistry images of liver sections from sham, control and lovastatin-treated animals 48 h after partial hepatectomy (PH). As can be seen immunohistochemistry, images never detect the IR in the hepatocyte nucleus in sham and lovastatin-treated group (observe the membrane concentration of IR) (top and bottom) but occasionally detect it in control animals (middle) 48 h after PH. Arrows: IR staining on cell membrane or in hepatocyte nuclei; scale bar = 40 µm. Objective lens: ×100.