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. 2018 Aug 20;9:675. doi: 10.3389/fneur.2018.00675

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Copyright © 2018 Chen, Wu, Wang and Luo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The results of neuropsychological tests related to frontoparietal cognitive function in the patients with anti-NMDAR encephalitis and health controls (HCs). (A,B) The patients showed demonstrated obvious improvements during the recovery period, but significant impairments were persisted at T1, T2 in digit span test and SDMT, and at T3 in digit span test. (C–E) The patients showed significant impairments at T1, and no obvious damage at T2, T3 in block design test, semantic fluency test and Stroop test. SDMT, symbol-digit modalities test. T1 = 1 to 2 months following initial immunotherapy. T2 = 6 months following initial immunotherapy. T3 = 11 to 12 months following initial immunotherapy. The two-sample t-test between the patients and health controls (HCs) at three time points. **p < 0.05/3; *p < 0.1/3 (Bonferroni correction).