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N-TIMP2HD inhibits U87MG xenograft growth in mice. Tumor size in mice treated with 500 nm N-TIMP2HD and in untreated (PBS) mice was monitored over 25 days. Measurements from days 4, 11, and 25 are shown. Each group contained five mice. At day 18, one mouse from the N-TIMP2HD-treated group died during anesthesia. Error bars represent S.E. Statistical analysis was performed by Student's t test compared with the PBS-treated control; *, p < 0.05; **, p < 0.001.
