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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: J Allergy Clin Immunol. 2018 Jan 10;142(2):605–617.e7. doi: 10.1016/j.jaci.2017.11.042

Figure 5. Partial restoration of NK cell function following initiation of rapamycin treatment in PI3K110δ patients.

Figure 5

A) NK cell number in three patients prior to (open squares) and following initiation of (open circles) rapamycin treatment. B) Evaluation of NK cell cytotoxic function without IL-2 stimulation in the same three patients relative to normal controls (dashed line). C) NK cell-target conjugates were analyzed as in Figure 4. **p<0.01 by Student’s two-tailed T test at 50:1 ratio. *p<0.05 by ordinary one-way ANOVA with post hoc comparison.