Table 2.
Growth curve models testing the impact of treatment outcomes (response/remission) and treatment condition on global functional outcomes
| Maximum Likelihood Effects | |||||||
|---|---|---|---|---|---|---|---|
| Response | Remission | ||||||
| CGAS/GAF | Q-LES-Q | Average HoNOS | CGAS/GAF | Q-LES-Q | Average HoNOS | ||
| Effect | Estimate (SE) | Estimate (SE) | Estimate (SE) | Effect | Estimate (SE) | Estimate (SE) | Estimate (SE) |
| Intercept | 62.66 (0.87)*** | 53.06 (0.63)*** | 0.78 (0.05)*** | Intercept | 62.91 (0.87)*** | 53.13 (0.61)*** | 0.78 (0.05)*** |
| Slope | −0.33 (0.57) | −0.34 (0.41) | −0.02 (0.03) | Slope | −0.52 (0.57) | −0.39 (0.41) | −0.02 (0.03) |
| Var (Intercept) | 85.78 (9.42)*** | 45.55 (5.88)*** | 0.20 (0.03)*** | Var (Intercept) | 86.28 (9.04)*** | 143.50 (45.00)*** | 0.20 (0.03)*** |
| Var (Slope) | 4.63 (1.59)** | 0.00 (0.00) | 0.00 (0.00) | Var (Slope) | 4.63 (1.58)** | 0.00 (0.00) | 0.00 (0.00) |
| Predictors of Intercept | Predictors of Intercept | ||||||
| Response status | 3.33 (1.53)* | 4.01 (1.26)** | −0.16 (0.08)* | Remission status | 4.12 (1.44)** | 3.73 (1.09)** | −0.22 (0.07)** |
| COMB Tx | 1.20 (2.16) | −2.21 (1.62) | 0.00 (0.11) | COMB Tx | 1.30 (2.05) | −1.56 (1.59) | 0.01 (0.10) |
| SRT Tx | 1.93 (2.03) | −0.77 (1.50) | −0.04 (0.10) | SRT Tx | 1.96 (2.00) | −0.54 (1.48) | −0.04 (0.10) |
| CBT Tx | 1.12 (2.09) | −1.05 (1.73) | −0.01 (0.11) | CBT Tx | 1.37 (2.02) | −0.58 (1.65) | −0.02 (0.10) |
| Sex | 3.43 (1.34)* | 1.82 (1.03) | −0.14 (0.07)* | Sex | 3.45 (1.33)** | 1.78 (1.03) | −0.14 (0.07)* |
| SES | 0.15 (0.07)* | 0.12 (0.05)* | −0.01 (0.00)* | SES | 0.15 (0.06)* | 0.12 (0.05)* | −0.01 (0.00)* |
| Ethnicity | −3.02 (2.93) | 0.48 (2.36) | 0.06 (0.14) | Ethnicity | −3.01 (2.95) | 0.51 (2.38) | 0.06 (0.15) |
| Baseline CGAS | 0.14 (0.14) | 0.16 (0.09) | −0.01 (0.01) | Baseline CGAS | 0.11 (0.14) | 0.14 (0.09) | 0.00 (0.01) |
| Baseline CGI-S | −0.23 (1.22) | 0.97 (0.89) | 0.04 (0.06) | Baseline CGI-S | 0.13 (1.22) | 1.20 (0.92) | 0.01 (0.06) |
| Visit 1 Age | 0.02 (0.24) | −0.25 (0.20) | 0.00 (0.01) | Visit 1 Age | −0.03 (0.24) | −0.27 (0.20) | 0.00 (0.01) |
| Predictors of slope | Predictors of slope | ||||||
| Response status | −0.11 (0.70) | −1.13 (.51)* | −0.03 (0.03) | Remission status | −0.24 (0.66) | −0.68 (0.46) | −0.02 (0.03) |
| COMB Tx | −0.27 (.95) | 1.38 (0.73) | −0.03 (0.04) | COMB Tx | −0.21 (0.87) | 1.06 (0.71) | −0.04 (0.04) |
| SRT Tx | −0.25 (0.82) | 0.80 (0.69) | −0.04 (0.04) | SRT Tx | −0.23 (0.82) | 0.71 (0.70) | −0.05 (0.04) |
| CBT Tx | 0.84 (0.87) | 1.72 (0.73)* | −0.09 (0.04)* | CBT Tx | 0.86 (0.85) | 1.56 (0.72)* | −0.09 (0.04)* |
| Gender | −0.05 (0.60) | −0.51 (0.43) | 0.04 (0.03) | Gender | −0.06 (0.60) | −0.46 (0.43) | 0.04 (0.03) |
| SES | 0.02 (0.03) | 0.00 (0.02) | 0.00 (0.00) | SES | 0.02 (0.03) | 0.00 (0.02) | 0.00 (0.00) |
| Ethnicity | 1.59 (1.14) | −0.75 (0.86) | 0.00 (0.06) | Ethnicity | 1.61 (1.14) | −0.81 (0.84) | −0.01 (0.06) |
| Baseline CGAS | 0.06 (0.06) | 0.00 (0.04) | 0.00 (0.00) | Baseline CGAS | 0.06 (0.06) | 0.01 (0.04) | 0.00 (0.00) |
| Baseline CGI-S | 0.02 (0.54) | −0.37 (0.38) | −0.02 (0.03) | Baseline CGI-S | −0.01 (0.55) | −0.36 (0.38) | −0.02 (0.03) |
| Visit 1 Age | 0.07 (0.09) | 0.10 (0.08) | 0.00 (0.01) | Visit 1 Age | 0.06 (0.09) | 0.12 (0.08) | 0.00 (0.01) |
Note. CGAS/GAF = Children’s Global Assessment Scale and Global Assessment of Functioning; CGI-S = Clinical Global Impression-Severity; Q-LES-Q = Quality of Life Enjoyment and Satisfaction Questionnaires; HoNOS = Health of the Nation Outcome Scales, Average HoNOS = Average score across all HoNOS subscales, higher numbers indicate greater impairment; Var = Residual Variance; COMB Tx = CAMS medication and therapy treatment condition; SRT Tx = CAMS medication treatment condition; CBT Tx = CAMS therapy treatment condition; Gender: 0 = Female, 1 = Male; Ethnicity: 0 = Non-Hispanic, 1 = Hispanic;
***
p<.001
**
p<.01
*
p<.05.