Table 3.
Linear Growth curve models testing the impact of remission status and treatment condition on domain-specific functional outcomes
| Maximum Likelihood Effects | ||||||
|---|---|---|---|---|---|---|
| HoNOS subscales | Milestones | |||||
| Effect | Social/Peer Relationships Estimate (SE) | Family life Estimate (SE) | School Performance Estimate (SE) | School Attendance Estimate (SE) | Occupation/Activities (n = 213) Estimate (SE) | Independent Living Estimate (SE) |
| Intercept | 1.10 (0.07)*** | 1.23 (0.07)*** | 0.59 (0.07)*** | 0.27 (0.06)*** | 0.18 (0.08)** | -- |
| Slope | 0.03 (0.05) | −0.15 (0.05)** | −0.06 (0.04) | 0.05 (0.05) | 0.05 (0.05) | 0.84 (0.34)* |
| Var (Intercept) | 0.53 (0.06)*** | 0.41 (0.06)*** | 0.25 (0.06)*** | 0.11 (0.04)** | 0.09 (0.05) | 4.70 (1.38)** |
| Var (Slope) | 0.00 (0.00) | 0.00 (0.00) | 0.00 (0.00) | 0.00 (0.00) | 0.00 (0.00) | 0.00 (0.00) |
| Predictors of intercept | ||||||
| Remission status | −0.30 (0.13)* | −0.14 (0.13) | −0.28 (0.12)* | 0.02 (0.11) | −0.30 (0.17) | −0.57 (0.54) |
| COMB Tx | −0.20 (0.19) | 0.09 (0.19) | 0.13 (0.19) | 0.09 (0.16) | 0.04 (0.21) | 0.16 (0.89) |
| SRT Tx | −0.14 (0.20) | 0.00 (0.17) | 0.06 (0.18) | 0.19 (0.15) | −0.20 (0.20) | −0.44 (0.80) |
| CBT Tx | −0.14 (0.20) | 0.01 (0.18) | 0.09 (0.17) | −0.04 (0.15) | 0.24 (0.27) | −1.22 (0.77) |
| Sex | −0.21 (0.12) | −0.43 (0.11)*** | 0.05 (0.10) | −0.01 (0.10) | −0.23 (0.12) | −0.26 (0.52) |
| SES | −0.01 (0.01) | 0.00 (0.01) | −0.01 (0.01)* | −0.01 (0.01)* | 0.00 (0.01) | 0.09 (0.04)* |
| Ethnicity | 0.02 (0.27) | −0.14 (0.24) | 0.25 (0.22) | 0.06 (0.20) | 0.29 (0.30) | −2.47 (1.33) |
| Baseline CGAS | −0.02 (0.01) | 0.00 (0.01) | −0.01 (0.01) | 0.01 (0.01) | 0.01 (0.01) | 0.12 (0.05)* |
| Baseline CGI-S | 0.04 (0.11) | 0.11 (0.11) | −0.15 (0.10) | 0.10 (0.00) | −0.03 (0.14) | 0.37 (0.51) |
| Visit 1 Age | 0.02 (0.02) | −0.04 (0.02) | −0.02 (0.02) | −0.01 (0.02) | 0.05 (0.02)** | 0.75 (0.17)*** |
| Predictors of slope | ||||||
| Remission status | −0.05 (0.05) | 0.00 (0.06) | −0.03 (0.06) | −0.06 (0.06) | 0.12 (0.08) | 0.00 (0.31) |
| COMB Tx | 0.01 (0.07) | −0.14 (0.09) | −0.06 (0.09) | −0.02 (0.10) | 0.01 (0.09) | 0.00 (0.30) |
| SRT Tx | −0.10 (0.07) | −0.06 (0.09) | −0.04 (0.09) | −0.11 (0.09) | 0.10 (0.10) | 0.00 (0.15) |
| CBT Tx | −0.08 (0.07) | −0.09 (0.09) | −0.18 (0.09)* | −0.04 (0.09) | −0.17 (0.11) | 0.00 (0.44) |
| Sex | 0.03 (0.05) | 0.08 (0.05) | 0.06 (0.05) | 0.03 (0.06) | 0.11 (0.07) | 0.00 (0.12) |
| SES | 0.00 (0.00) | 0.00 (0.00) | 0.00 (0.00) | 0.00 (0.00) | 0.00 (0.00) | 0.00 (0.03) |
| Ethnicity | 0.02 (0.09) | 0.15 (0.10) | −0.14 (0.12) | −0.14 (0.10) | −0.21 (0.15) | 0.00 (0.51) |
| Baseline CGAS | 0.00 (0.01) | 0.00 (0.01) | 0.00 (0.01) | −0.01 (0.01) | −0.01 (0.01) | 0.00 (0.05) |
| Baseline CGI-S | −0.04 (0.05) | −0.02 (0.05) | 0.01 (0.06) | 0.00 (0.04) | −0.02 (0.07) | 0.00 (0.19) |
| Visit 1 Age | 0.00 (0.01) | −0.01 (0.01) | −0.02 (0.01) | 0.00 (0.01) | −0.01 (0.01) | 0.00 (0.05) |
Note. HoNOS = Health of the Nation Outcome Scales, higher scores indicate greater impairment; CGI-S = Clinical Global Impression-Severity; CGAS = Children’s Global Assessment Scale; Var = Residual Variance; COMB tx = CAMS medication and therapy treatment condition; SRT tx = CAMS medication treatment condition; CBT tx = CAMS therapy treatment condition; Gender: 0 = Female, 1 = Male; Ethnicity: 0 = Non-Hispanic, 1 = Hispanic;
***
p<.001
**
p<.01
*
p<.05.