Table 4.
Quadratic growth curve models testing the impact of remission status and treatment condition on domain-specific functional outcomes
| Maximum Likelihood Effects | ||
|---|---|---|
| HoNOS subscale | Milestones | |
| Effect | Self-care/Independence Estimate (SE) | Employment Estimate (SE) |
| Intercept | 0.59 (0.05)*** | −0.69 |
| Linear Slope | −0.09 (0.07) | −0.55 (0.34) |
| Quadratic Slope | 0.04 (0.02) | 0.18 (0.11) |
| Var (Intercept) | 0.21 (0.04)*** | 3.59 (0.996)*** |
| Var (Linear Slope) | 0.00 (0.00) | 0.00 (0.00) |
| Var (Quadratic Slope) | 0.00 (0.00) | 0.00 (0.00) |
| Predictors of intercept | ||
| Remission status | −0.35 (0.10)*** | 0.82 (0.41)* |
| COMB Tx | 0.14 (0.14) | 0.39 (0.63) |
| SRT Tx | 0.02 (0.14) | −0.59 (0.64) |
| CBT Tx | 0.12 (0.14) | −0.28 (0.56) |
| Sex | −0.06 (0.09) | 0.05 (0.37) |
| SES | −0.01 (0.00) | 0.13 (0.09) |
| Ethnicity | 0.35 (0.22) | 0.64 (0.66) |
| Baseline CGAS | 0.00 (0.01) | −0.002 (0.03) |
| Baseline CGI-S | 0.04 (0.08) | 0.70 (0.34)* |
| Visit 1 Age | 0.02 (0.02) | 0.63 (0.09)*** |
| Predictors of linear slope | ||
| Remission status | 0.08 (0.14) | −0.54 (0.09)*** |
| COMB Tx | −0.12 (0.21) | 0.38 (0.14)** |
| SRT Tx | −0.31 (0.20) | −0.18 (0.14) |
| CBT Tx | −0.21 (0.22) | 1.26 (0.14)*** |
| Sex | 0.11 (0.13) | −0.48 (0.08)*** |
| SES | 0.00 (0.01) | −0.03 (0.02) |
| Ethnicity | −0.29 (0.27) | −1.15 (0.22)*** |
| Baseline CGAS | 0.00 (0.01) | −0.03 (0.01)** |
| Baseline CGI-S | −0.18 (0.11) | −0.25 (0.08)** |
| Visit 1 Age | −0.03 (0.02) | −0.10 (0.01)*** |
| Predictors of quadratic slope | ||
| Remission status | −0.02 (0.05) | 0.24 (0.07)** |
| COMB Tx | 0.00 (0.08) | −0.25 (0.12)* |
| SRT Tx | 0.08 (0.08) | −0.02 (0.12) |
| CBT Tx | 0.02 (0.08) | −0.44 (0.11)*** |
| Sex | −0.05 (0.04) | 0.08 (0.07) |
| SES | 0.00 (0.00) | 0.01 (0.02) |
| Ethnicity | 0.15 (0.09) | 0.26 (0.17) |
| Baseline CGAS | 0.00 (0.00) | 0.01 (0.01) |
| Baseline CGI-S | 0.06 (0.04) | 0.08 (0.06) |
| Visit 1 Age | 0.01 (0.01) | 0.01 (0.01) |
Note. HoNOS = Health of the Nation Outcome Scales, higher scores indicate greater impairment; CGI-S = Clinical Global Impression-Severity; CGAS = Children’s Global Assessment Scale; Var = Residual Variance; COMB tx = CAMS medication and therapy treatment condition; SRT tx = CAMS medication treatment condition; CBT tx = CAMS therapy treatment condition; Gender: 0 = Female, 1 = Male; Ethnicity: 0 = Non-Hispanic, 1 = Hispanic;
***
p<.001
**
p<.01
*
p<.05.