Skip to main content
. 2018 Aug 24;6:e5503. doi: 10.7717/peerj.5503

Table 1. The characteristics of different types of CircRNA.

Name Type Location Joint site Sequence feature Function
ecRNA (Zhang et al., 2014) exon cytoplasms 3′–5′ phosphodiester bond Formed by cyclization of exons containing the reverse complementary sequence of introns and selective cyclization. Functioning as miRNA sponges; Interact with RNA-binding proteins (RBPs); Participates in translation.
CiRNA (Zhang et al., 2013) intron nucleus 2′-5′ phosphodiester bond 5′ splice site enriched with 7 GU motifs and 3′ branch site contains 11 C motifs. Regulation of gene transcription.
ElciRNA (Li et al., 2017b) exon–intron nucleus 3′-5′ phosphodiester bond Formed by cyclization of exons containing the reverse complementary sequence of introns and selective cyclization. Regulation of gene transcription.

Notes:

ecRNA, exon circRNA; ciRNA, intron circRNA; ElciRNA, exon-intron circRNA.