Table S2.
Demographic characteristics and mean scores according to level of education
| Low-level education group
| ||||||
|---|---|---|---|---|---|---|
| Index (mean ± SD) | NC (n=82) | MCI (n=96) | Mild AD (n=80) | Moderate AD (n=132) | F (P) | P-value |
| Age | 68.2±8.8 | 67.5±8.2 | 68.2±7.6 | 68.4±8.5 | 0.869 | – |
| Education, years | 3.9±2.3 | 4.0±2.1 | 4.5±2.1 | 3.7±2.2 | 0.135 | – |
| Sex (M/F) | 27/55 | 37/59 | 28/52 | 43/89 | – | sig 0.800 |
| MMSE total score | 27.1±2.6 | 25.3±2.5 | 20.9±2.8 | 15.8±2.8 | <0.001 | <0.001 |
| MoCA-BC-T score | 20.6±4.7 | 16.4±3.8 | 12.9±3.0 | 8.7±3.7 | <0.001 | <0.001 |
| MoCA-BC-MIS score | 9.7±4.5 | 4.5±3.9 | 2.5±3.4 | 1.2±2.4 | <0.001 | <0.001 |
| MoCA-BC-NM score | 12.4±2.1 | 11.0±2.1 | 9.2±2.1 | 6.7±2.4 | <0.001 | <0.001 |
|
| ||||||
|
Mid-level education group
| ||||||
| Index (mean ± SD) | NC (n=285) | MCI (n=379) | Mild AD (n=180) | Moderate AD (n=225) | F (P) | P-value |
|
| ||||||
| Age | 67.8±8.3 | 66.9±8.3 | 68.6±9.2 | 68.5±9.5 | 0.080 | – |
| Education, years | 10.1±1.9 | 10.2±1.7 | 10.4±1.5 | 10.1±1.5 | 0.314 | – |
| Sex (M/F) | 87/198 | 165/214 | 79/101 | 106/119 | – | sig <0.001 |
| MMSE total | 28.0±1.5 | 26.5±1.7 | 22.0±1.3 | 16.4±2.8 | <0.001 | <0.001 |
| MoCA-BC-T | 24.4±2.6 | 19.6±3.5 | 14.7±3.5 | 9.6±3.5 | <0.001 | <0.001 |
| MoCA-BC-MIS | 10.4±3.3 | 5.1±3.9 | 1.8±2.8 | 0.9±1.9 | <0.001 | <0.001 |
| MoCA-BC-NM | 13.7±1.2 | 12.3±1.7 | 9.9±2.0 | 7.0±2.2 | <0.001 | <0.001 |
|
| ||||||
|
High-level education group
| ||||||
| Index (mean ± SD) | NC (n=153) | MCI (n=188) | Mild AD (n=85) | Moderate AD (n=84) | F (P) | P-value |
|
| ||||||
| Age | 71.0±7.5 | 71.2±8.3 | 71.7±8.4 | 72.3±7.9 | 0.607 | – |
| Education, years | 15.3±1.2 | 15.4±1.2 | 15.2±1.5 | 15.1±1.1 | 0.108 | – |
| Sex (M/F) | 64/89 | 103/85 | 55/30 | 45/39 | – | sig 0.006 |
| MMSE total | 28.1±1.6 | 26.6±1.7 | 22.7±1.5 | 16.9±2.7 | <0.001 | <0.001 |
| MoCA-BC-T | 25.3±2.6 | 20.4±3.3 | 15.2±4.0 | 10.6±3.9 | <0.001 | <0.001 |
| MoCA-BC-MIS | 10.2±3.7 | 4.3±3.9 | 1.9±2.4 | 0.8±1.8 | <0.001 | <0.001 |
| MoCA-BC-NM | 13.9±1.0 | 12.5±1.6 | 10.0±2.3 | 7.4±2.3 | <0.001 | <0.001 |
Note: NC vs MCI, NC vs mild AD, NC vs moderate AD, MCI vs mild AD, MCI vs moderate AD, mild AD vs moderate AD.
Abbreviations: MMSE, mini-mental state examination; MoCA-BC, Chinese version of Montreal Cognitive Assessment Basic; NC, cognitively normal controls; MCI, mild cognitive impairment; AD, Alzheimer’s disease; MoCA-BC-T, total score of MoCA-BC; MoCA-BC-MIS, the Memory Index Score of MoCA-BC; MoCA-BC-NM, the Non-memory Index Score of MoCA-BC.