Figure 1. Proportion of Individuals With Acute Kidney Injury (AKI) by Acetaminophen Exposure and Dose.

A, The proportion (percentage) of individuals with early postoperative AKI is shown for those administered no acetaminophen or at least 1 dose of acetaminophen in the first 48 hours after surgery. B, The proportion (percentage) of individuals with early postoperative AKI is shown for those with no acetaminophen administered in the first 48 hours after surgery and for the lowest (<40 mg/kg), middle (40-80 mg/kg), and highest (>80 mg/kg) cumulative doses of acetaminophen in the first 48 hours after surgery. P values are from the Pearson χ² test across all groups.

^aP < .001 across all 4 groups.

^bP = .42 across all 4 groups.