Table 1. Characteristics of the Primary and Validation Cohorts.
| Variable | Primary Cohort (n = 666) | Validation Cohort (n = 333) |
|---|---|---|
| Age, median (IQR), mo | 6.5 (3.9-44.7) | 14.1 (3.9-158.2) |
| Female sex, No. (%) | 328 (49.2) | 172 (51.7) |
| Weight, median (IQR), kg | 7.1 (5.0-14.6) | 9.2 (4.7-49.0) |
| Serum creatinine, median (IQR), mg/dL | ||
| Preoperative baseline | 0.35 (0.25-0.45) | 0.30 (0.20-0.60) |
| Postoperative peak | 0.53 (0.45-0.66) | 0.50 (0.40-0.90) |
| RACHS score, No./total No. (%)a | ||
| 1 | 143/636 (22.5) | 88/273 (32.2) |
| 2 | 256/636 (40.3) | 112/273 (41.0) |
| ≥3 | 237/636 (37.3) | 73/273 (26.7) |
| CPB time, median (IQR), minb | 87 (59-122) | 95 (39-149) |
| AKI outcome, No. (%) | ||
| No AKI | 325 (48.8) | 171 (51.4) |
| Stage 1 | 159 (23.9) | 51 (15.3) |
| Stage 2 | 131 (19.7) | 91 (27.3) |
| Stage 3 | 51 (7.7) | 20 (6.0) |
Abbreviations: AKI, acute kidney injury; CPB, cardiopulmonary bypass; IQR, interquartile range; RACHS, Risk Adjustment for Congenital Heart Surgery.
SI conversion factor: To convert creatinine level to micromoles per liter, multiply by 88.4.
a
Score available for 636 in the primary cohort and 273 in the validation cohort.
b
Time available for 665 in the primary cohort and all 333 in the validation cohort.