Table 3. Estimated relative risk for decline of eGFR ≥ 40% by repeatedly measured albuminuria.

	B	S.E.	EXP (B)	95% CI of Wald		P value
Gender (female)	-0.232	0.772	0.792	-1.746	1.282	0.764
Age (year)	0.011	0.035	1.011	-0.057	0.079	0.749
eGFR (ml/min/1.73 m2)	-0.043	0.020	0.976	-0.083	-0.003	0.035
Repeatedly measured albuminuria (per 500mg/day)	0.375	0.107	1.455	0.165	0.585	<0.001

eGFR, estimated glomerular filtration rate; S.E., standard error.

The model using the generalized estimating equations was adjusted for age, sex, and independent factors related to the risk of a decline of eGFR ≥ 40% such as eGFR level during the enrollment period of the trial phase.