Fig 7. The levels of individual species of galactosylceramides, GalCer, during remyelination in the presence of vitamin K, were determined by mass spectrometry.
The remyelination took place for either 1 week or 3 weeks in the presence of vitamin K. The levels of brain GalCer (C18:0) (A), GalCer (C20:0) (B), GalCer (C24:0) (C), and GalCer (C24:1) (D) were measured in the brain samples of mice that remyelinated for either 1 week or 3 weeks while receiving vitamin K injections as described under the Materials and Methods section. n = 4 mice per group, and concentrations are expressed as mean ± SEM. *P < 0.05, **P < 0.01. Please see the text for the actual P-values.