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A. A schematic diagram showing the synthesis of sulfatides from ceramide, and how the production of sulfatides during remyelination may be affected by a vitamin K-deficiency. B. The structure of d18:1/C24:1 sulfatide, which is a major myelin sulfatide. Vitamin K increases the synthesis of this sulfatide, among other sulfatides, after 3 weeks of remyelination. This sulfatide is composed of a ceramide moiety containing 4-sphingenine (d18:1) with a C24:1 fatty acid.
