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. 2018 Aug 27;13(8):e0202977. doi: 10.1371/journal.pone.0202977

Table 3. Hazard ratios f of interactions among psychosocial hazards or on CVD classified by psychosocial hazards in participants (n = 707).

 Dependent variable Univariate Analysis Multivariate Analysis
Model 1 HR 95%CI p-value HR 95%CI p-value
    Long working hours 1.76 1.11 2.81 0.017 1.65 1.03 2.66 0.037
    High job stress 1.03 0.56 1.87 0.936 0.94 0.51 1.74 0.852
    High fatigue 1.31 0.81 2.12 0.280 1.43 0.87 2.36 0.160
    MetS 1.69 1.07 2.67 0.025 1.33 0.77 2.29 0.308
Model 2
    Ref: Working hours < = 12 hrs and SSOS = +2
    Either long working hours or high job stress only 1.80 0.83 3.89 0.135 1.64 0.76 3.57 0.210
    Both long working hours and high job stress 2.48 1.14 5.37 0.022 2.17 0.99 4.79 0.054
    MetS 1.69 1.07 2.67 0.025 1.33 0.77 2.30 0.302
Model 3
    Ref: Working hours < = 12 hr & SOFI<3
    Either long working hours or high fatigue only 1.27 0.71 2.28 0.419 1.35 0.75 2.43 0.321
    Both long working hours and high fatigue 2.29 1.28 4.09 0.005 2.31 1.26 4.23 0.007
    MetS 1.69 1.07 2.67 0.025 1.32 0.77 2.26 0.321
Model 4
    Ref: SSOS = +2 & SOFI<3
    Either high job stress or high fatigue only 2.10 0.92 4.77 0.078 1.90 0.83 4.35 0.130
    Both high job stress and high fatigue 2.15 0.96 4.83 0.064 2.07 0.90 4.73 0.086
    MetS 1.70 1.08 2.69 0.022 1.32 0.76 2.27 0.321
Model 5
    Ref: Working hours < = 12 hr & SSOS = +2 & SOFI<3
    One of three variables (long working hours, high job stress, or high fatigue) 2.76 0.95 8.02 0.062 2.43 0.83 7.08 0.105
    Two of three variables (long working hours, high job stress, or high fatigue) 2.66 0.92 7.67 0.070 2.57 0.89 7.45 0.082
    All of three variables (long working hours, high job stress, or high fatigue) 4.10 1.42 11.80 0.009 3.71 1.26 10.91 0.017
    MetS 1.69 1.07 2.67 0.025 1.31 0.76 2.26 0.331

Long working hours = driving hour>12 hour/ day; High job stress = SSOS_scores < +1; High fatigue = SOFI > = 3.

CVD, cardiovascular and cerebrovascular diseases; HR, hazard ratios; CI, confidence interval; MetS, metabolic syndrome; SSOS, Stress Satisfaction Offset Score; SOFI, Swedish Occupational Fatigue Inventory.

a. Adjusted for age, BMI, education, drinking, smoking, and exercise.