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. 2001 Nov 6;98(24):13710–13715. doi: 10.1073/pnas.231370798

Figure 3.

Figure 3

Effects of H-89 and cantharidic acid on transcription activity of L-PK gene in ChREBP-overexpressed hepatocytes. Rat primary cultured hepatocytes were transfected with the WT ChREBP. H-89, cantharidic acid, or dimethyl sulfoxide vehicle was added, and the cells were incubated in 5.5 mM (□) or 27.5 mM (■) glucose for 12 h. Relative luciferase activity was calculated as described in Experimental Procedures and is expressed as mean ± SEM (n = 5). *, P < 0.05 compared with that of WT ChREBP.