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. 2018 Jul 23;17(10):1199–1211. doi: 10.1080/15384101.2018.1469872

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Figure 2. — PTC-209 inhibits glioblastoma cell proliferation and results in cell cycle arrest. (A) Chemical structure of PTC-209. (B) Western blot analysis of U87MG cell lysates following PTC-209 (1 μM and 10 μM) or vehicle control (DMSO) treatment for 4 days. (C) Cell proliferation assay results for PTC-209 (1 μM and 10 μM) or DMSO treated U87MG and T98G cells (mean ± SD; n = 6; ***p < 0.001). (D) U87MG and T98G cells treated with PTC-209 (1 μM and 10 μM) or DMSO for 4 days were analyzed by flow cytometry-based propidium iodide staining. Graphs represent the mean of 3 independent experiments.