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. 2018 Aug 21;11:5035–5043. doi: 10.2147/OTT.S170439

Figure 2.

Figure 2

Knockdown of XIST inhibits cell proliferation of PTC cells.

Notes: (A) qRT-PCR was performed to examine the expression levels of XIST in TPC-1 cells transfected with si-XIST or si-NC. (B) CCK-8 assay was performed to examine cell proliferation in TPC-1 cells transfected with si-XIST or si-NC. (C) Flow cytometric analysis was conducted to analyze the cell cycle arrest in TPC-1 cells transfected with si-XIST or si-NC. **P<0.01. Data are expressed as the mean ± SD of at least three independent experiments.

Abbreviations: XIST, X-inactive specific transcript; PTC, papillary thyroid carcinoma; qRT-PCR, quantitative real-time polymerase chain reaction; NC, negative control; CCK, Cell Counting Kit; OD, optical density.