Table 1.
Correlation between clinicopathological features and XIST expression in 36 patients with PTC
| Variables | No. of cases |
XIST expression
|
P-value | |
|---|---|---|---|---|
| High, n (%) | Low, n (%) | |||
| Age, years | P>0.05 | |||
| <60 | 15 | 9 (60.0) | 6 (40.0) | – |
| ≥60 | 21 | 11 (52.3) | 10 (47.7) | – |
| Gender | P>0.05 | |||
| Male | 13 | 7 (53.8) | 6 (46.2) | – |
| Female | 23 | 13 (56.5) | 10 (42.5) | – |
| TNM stage | P<0.01 | |||
| I–II | 28 | 12 (42.9) | 16 (57.1) | – |
| III–IV | 8 | 8 (100) | 0 (0) | – |
| Tumor size | P>0.05 | |||
| <5 cm | 26 | 14 (53.8) | 12 (46.2) | – |
| ≥5 cm | 10 | 6 (60.0) | 4 (40.0) | – |
| Lymph node metastasis | P<0.01 | |||
| No | 27 | 12 (44.4) | 15 (55.6) | – |
| Yes | 9 | 8 (88.9) | 1 (10.1) | – |
Abbreviations: PTC, papillary thyroid carcinoma; XIST, X-inactive specific transcript.