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. 2018 Sep;43(9):549–556.

Table 3.

Monitoring Parameters for PARP Inhibitors

PARP Inhibitor (Generic Name) Indication for Monitoring Labs and Monitoring Schedule
Niraparib34 Bone marrow suppression AML/MDS Monitor CBC weekly for first month, then monthly for the following 11 months, then periodically
Cardiovascular events Monitor BP and HR monthly for first year of therapy, then periodically
Olaparib35 Bone marrow suppression AML/MDS Monitor CBC at baseline, then monthly
Pneumonitis Monitor for signs and symptoms of pneumonitis
Rucaparib37 Bone marrow suppression AML/MDS Monitor CBC at baseline, then monthly

AML = acute myeloid leukemia; BP = blood pressure; CBC = complete blood count; HR = heart rate; MDS = myelodysplastic syndrome.