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. 2018 Aug 27;8:12830. doi: 10.1038/s41598-018-31169-z

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Improvement of visual acuity. (A) Scatter plots showing each individual patient’s visual acuity (amblyopic eye) at baseline, at week 10 (end of treatment/training) and at week 22 (end of follow-up), as measured by ETDRS chart (logMAR). Control group is shown on the left and fluoxetine group on the right. The limit of normal visual acuity (logMAR 0) is shown with a hatched line. (B) Average change in visual acuity from baseline as measured by ETDRS chart (logMAR) at baseline and after 2, 6, 10, 14 and 22 weeks. Average +/− 95% CI in each timepoint when visual acuity was determined by ETDRS chart is shown. (C) Number of patients per group who showed improved visual acuity by ≥0.2 or <0.2 logMAR units at week 10 and 22 as compared to baseline.