Table 2.

Demographic and clinical characteristics of subjects.

	AD (N = 11)	MCI (N = 8)	Normal (N = 21)
Age (years)	67 (10) [49–83]	69 (7) [59–77]	46 (11) [28–77]
Sex (male/female)	5/6	7/1	12/9
MMSE score	22 (5) [13–28]	26 (3) [21–30]	N.A.
CSF Aβ1−42/p-tau ratio	6.03 (0.96) [4.8–7.8]	5.79 (2.3) [0.72–8.01]	8.2 (1.4) [6.03–10.47]
CSF/serum urea ratio	0.85 (0.07 [0.73–0.93]	0.98 (0.18) [0.78–1.34]	0.79 (0.15) [0.53–1.10]
CSF/serum creatinine ratio	1.15 (0.14) [0.93–1.40]	1.13 (0.20) [0.85–1.38]	1.5 (0.4) [0.9–2.2]
CSF/serum albumin ratio	0.66 (0.34) [0.22–1.32]	1.2 (1.8) [0.2–5.1]	0.45 (0.24) [0.15–1.06]

All statistics are mean (standard deviation) [range].

AD, Alzheimer's disease; MCI, mild cognitive impairment.

MMSE, Mini-Mental State Examination.

CSF, cerebrospinal fluid.