Table 1.
Level of bias of included studies
| Random sequence generation | Allocation concealment | Blinding of participants and personnel | Blinding of outcome assessors | Incomplete outcome data | Selective reporting | Other bias | |
|---|---|---|---|---|---|---|---|
| DB2113360 | Low | Low | Low | Low | Low | Low | Low |
| DB2113374 | Low | Low | Low | Low | Low | Low | Low |
| ZEP117115 | Low | Low | Low | Low | Low | Low | Low |
| DB2116960 | Low | Low | Low | Low | Low | Low | Low |
| PINNACLE 1 | Low | Low | High | High | Unclear | Low | Low |
| TONADO 1 | Low | Low | Low | Unclear | Unclear | Low | Unclear |
| TONADO 2 | Low | Low | Low | Unclear | Unclear | Low | Unclear |
| OTEMTO 1 | Unclear | Unclear | Low | Unclear | Unclear | Low | Low |
| OTEMTO 2 | Unclear | Unclear | Low | Unclear | Unclear | Low | Low |