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. 2018 Aug 27;8:12890. doi: 10.1038/s41598-018-31270-3

Table 3.

Comparison of the serum parameters for oxidative stress and antioxidants.

Measurements Healthy subjects
(Total 82, M 27/F 55)
ICF subjects
(Total 103, M 20/F 83)
TAC (μM)
Male/Female
312.8 ± 55.6
325.5 ± 56.8/307.2 ± 54.8
232.8 ± 46.6**
231.7 ± 44.7**/233.0 ± 47.4**
Catalase (unit/mL)
Male/Female
337.4 ± 193.8
401.2 ± 203.0/300.5 ± 180.4
197.0 ± 72.6**
246.6 ± 45.2**/183.9 ± 73.0**
SOD (unit/mL)
Male/Female
2.4 ± 0.9
2.4 ± 0.9/2.4 ± 1.0
1.6 ± 0.7**
1.5 ± 0.8**/1.6 ± 0.7**
Total GSH contents (μM)
Male/Female
54.6 ± 48.5
68.4 ± 59.3/46.2 ± 39.0
28.8 ± 37.1**
42.5 ± 24.6/24.9 ± 39.1**
GSH/GSSG ratio
Male/Female
14.6 ± 4.2
17.8 ± 3.1/11.8 ± 2.8
11.1 ± 2.5**
13.4 ± 1.5**/9.6 ± 2.8*
GSH-peroxidase (unit/mL)
Male/Female
0.81 ± 0.86
0.81 ± 0.58/0.81 ± 0.95
0.36 ± 0.14*
0.37 ± 0.16*/0.36 ± 0.14
GSH-reductase (unit/mL)
Male/Female
0.52 ± 0.12
0.62 ± 0.12/0.47 ± 0.10
0.23 ± 0.10**
0.13 ± 0.07**/0.26 ± 0.09**
HO-1 (ng/mL)
Male/Female
1.8 ± 0.8
1.9 ± 1.0/1.7 ± 0.7
2.0 ± 0.9
2.7 ± 1.1*/1.8 ± 0.6
TNF-alpha (pg/mL)
Male/Female
23.9 ± 16.4
21.4 ± 10.4/25.0 ± 18.3
57.2 ± 42.5**
54.2 ± 45.8**/58.0 ± 41.9**
IFN-gamma (pg/mL)
Male/Female
30.3 ± 28.0
30.6 ± 28.0/30.2 ± 28.4
25.3 ± 39.3
33.6 ± 69.2/22.9 ± 25.9

Data are expressed as the average ± SD. **The statistical significance between healthy and ICF was observed as *p < 0.05 or **p < 0.01.