FIGURE 4.

Modulation of STEAP1 expression changes susceptibility to docetaxel treatment. (A) Firefly luciferase or STEAP1 overexpressing HMrSV5 cells were treated with indicated doses of docetaxel 72 h. (B) MKN45 cells transiently transfected with siRNA targeting Renilla luciferase or STEAP1 were treated with indicated doses of docetaxel for 72 h. MTT assay was performed to assess the cell viability after 72 h. Data was obtained from three independent replicates experiments and was represented as mean ± standard deviation (SD). ^∗p < 0.05.