Table 1.
Gene Ontology enrichment of modulated modularity clusters.
| Process/Module* | Function (GO term number) |
|---|---|
| METABOLISM | |
| 11 | Pyruvate metabolism (0006090) |
| 5 | Phosphorus/phosphate metabolism (0006793/0006796); negative regulation of macromolecule metabolism (0010605) |
| TRANSLATION | |
| 1 | Regulation of translational initiation (0006446) |
| 1,4,5,6,8,11 | Translation (0006412) |
| 1,5,6,8,11 | Translational initiation (0006413) |
| 8 | tRNA amino acylation for protein translation (0006418) |
| PROTEIN PROCESSING | |
| 2,4 | Protein localization (0008104) |
| 5 | Regulation of protein complex disassembly (0043244); protein amino acid phosphorylation (0006468) |
| 6 | Protein folding (0006457) |
| PROTEIN TRANSPORT | |
| 2 | Intracellular transport (0046907); vesicle-mediated transport (0016192); endosome transport (0016197) |
| 4 | Protein transport (0015031); establishment of protein localization (0045184) |
| PROTEIN METABOLISM | |
| 5 | Regulation of proteolysis (0030162); negative regulation of cellular protein metabolism (0032269/0051248); phosphorylation (0016310) |
| 8 | Amino acid activation (0043038); tRNA amino acylation (0043039) |
| 10 | Cytokine-mediated signaling pathway (0019221) |
| CELL CYCLE | |
| 4 | Cell cycle (0007049); cell division (0051301) |
| Hypoxia response | |
| 7 | Response to oxygen levels/hypoxia (0070482/0001666) |
*
Module 3 is not enriched for any Gene Ontology terms.