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. 2018 Aug 21;9:1160. doi: 10.3389/fphys.2018.01160

FIGURE 1.

FIGURE 1

Octopus bimaculoides and mouse neurogenesis occurs in similarly laminated neuroectoderm. (A) Schematic top–down overview of the neurogenic territories in the stage 8 Octopus bimaculoides embryo. All color-marked areas are neurogenic, cord-like regions. (B) Whole-mount in situ hybridization for NEUROD, a marker of young post-mitotic neurons. (C,D) Higher magnification of the neurogenic area (white dashed line in B) demarcating a laminated structure with post-mitotic neurons (pm, arrowhead, marked by NEUROD, C) separated from progenitors (pz, star, marked by NEUROG, D) (dashed line). (E) Schematic view of a coronal section through the mouse telencephalon at E13.5, demarcating the ventral telencephalon (vt, gray) and dorsally placed cortex (ctx) and hippocampal (hc) areas (green). (F) In situ hybridization of Neurod, a post-mitotic neuron proneural transcription factor. (G,H) Higher magnification of the cortical laminated structure (dashed lines), with a progenitor zone (pz, marked by Neurog2, H) lining the ventricle and a post-mitotic cortical plate (cp, marked by NeuroD, G). (B–D) Adapted from Shigeno et al. (2015). cc, cerebral cord; cp, cortical plate; ctx, cerebral cortex; ey, eye; hc, hippocampus; m, mantle; mo, mouth; olf, olfactory organ; opt, optic lobe; pedc, pedal cord; pvc, palliovisceral cord; pz, progenitor zone; sp, subpedunculate tissue; st, statocyst; vt, ventral telencephalon; ve, ventricle.