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. 2018 Aug 21;9:1951. doi: 10.3389/fmicb.2018.01951

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Copyright © 2018 Martins, Martins and Santos.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transmission electron microscopy of cells infected with viruses, showing LDs morphological changes. (A) Tamarin liver tissue uninfected and (B–D) infected with GB virus B, an unclassified flavivirus similar to HCV. Lipid droplets (pointed by →, and with electron-dense surface deposits), mitochondria () and the nucleus (N) can be identified. The scale bar corresponds to 1 μm. Most hepatocytes of the infected animal contain multiple small (ca. 2 μm diameter) LDs. They may be indicative of ongoing viral replication [reprinted from Martin et al. (2003). Copyright (2003) National Academy of Sciences, United States].

Inline graphic — Transmission electron microscopy of cells infected with viruses, showing LDs morphological changes. (A) Tamarin liver tissue uninfected and (B–D) infected with GB virus B, an unclassified flavivirus similar to HCV. Lipid droplets (pointed by →, and with electron-dense surface deposits), mitochondria () and the nucleus (N) can be identified. The scale bar corresponds to 1 μm. Most hepatocytes of the infected animal contain multiple small (ca. 2 μm diameter) LDs. They may be indicative of ongoing viral replication [reprinted from Martin et al. (2003). Copyright (2003) National Academy of Sciences, United States].