Table 7.

Quantification of white matter alterations in DM2.

Study	Modality	Estimated parameters	Group size	Age (M ±SD) [years]	Age at onset [years]	Control group	Disease duration (M ±SD) [years]	Correlation parameters
Minnerop et al. (11)	3T DTI	DTI-TBSS (FA, MD, RD, AD)	22 (22)	52.5 ± 10.1	-	+	11.9 ± 9.9	Age (+), disease duration (+), motor performance (+), depression (+), fatigue (+), NPT
Franc et al. (57)	3T DTI	DTI (FA), ROI-based	5 (5)	38–49	29.5	+	-	Masticatory muscle volume (+)

AD, axial diffusivity; DTI, diffusion tensor imaging; FA, fractional anisotropy; MD = mean diffusivity; NPT, neuropsychological tests; RD, radial diffusivity; ROI, region of interest; TBSS, tract-based spatial statistics; (+), positive or negative correlation was found.