Fig. 2.

(A) Liver of control mice showing normal appearance of the central vein (C) and hepatic parenchyml cells (H). (B) Liver of BPA treated mice showing congestion (C) of the hepatic blood vessels and marked vacuolar degeneration of the hepatocytes with many necrotic cells (arrow). (C) Liver of BPA treated mice showing congestion of the central vein (C) and portal blood vessels (P) with marked hepatocellular vacuolar degeneration and necrosis (arrow). (D) Liver of PSO treated mice before BPA treatment showing mild vacuolar degeneration of the hepatocytes with some necrotic cells (arrow). (E) Liver of PSO treated mice concurrently with BPA showing centrilobular degeneration (C) and necrosis of the hepatocytes, notice the karyomegaly of some cells (arrow). (F) Liver of PSO treated mice after BPA treatment showing granular degeneration and scattered necrotic hepatocytes (arrow). (H&E X400).