Fig. 5.

Caspase-3 activity in non-transfected and transfected U-87 MG cells. The effect of quercetin (at final concentrations of 10 and 30 μM) and rosmarinic acid (RA, at final concentrations of 80 and 215 μM) separately on the activation of caspase-3 was shown in the figure in non-transfected cells group. The effect of siRNA transfection and combined therapy on the activation of caspase-3 was shown in the figure in transfected cells group. Graph represents the mean ± SD (n = 6). *P < 0.05, **P < 0.01, ***P < 0.001 determined by one-way ANOVA using Dunnet’s multiple comparison test. C control, Q quercetin, RA rosmarinic acid, si siRNA