Table 2.

Effect of CUB-F1 supplementation on serum lipid profile, oxidative stress and antioxidant biomarkers in HL rats.

Biomarkers/Groups	Serum lipid profile				Oxidative stress and antioxidant biomarkers
	Parameters	TC (mg/dl)	TG (mg/dl)	TL (mg/dl)	MDA (mg/dl)	NO (µmol/l)	GSH (mg/dl)	TAC (Mm/l)
Negative control rats	Mean ± SD	60.58 ± 9.98a	40.47 ± 4.18a	1000.30 ± 16.23a	8.34 ± 0.99a	13.98 ± 0.79a	72.79 ± 4.56a	1.88 ± 0.10a
Hyperlipidemic rats (HL)	Mean ± SD	99.10 ± 5.12b	77.91 ± 3.28b	1889.13 ± 17.22b	11.64 ± 1.00b	19.99 ± 1.22b	49.4 ± 3.66b	0.945 ± 0.06b
	% change to C	+63.58	+92.51	+88.85	6.89 ± 0.94c	12.86 ± 1.09a	66.33 ± 10.28a	1.495 ± 0.08a
CUB-F1 treated rats	Mean ± SD	67.105 ± 7.90a	60.00 ± 8.22c	1113.96 ± 16.23a	−17.39	−8.01	−8.87	−20.48
	% change to C	+10.76	+48.26	+11.36	−40.80	−35.66	+34.27	+58.20
	% change to HL	−32.29	−22.98	−41.03	56.95	51.00	23.26	29.26
	%improvement	52.82	44.26	77.49	7.00 ± 0.67c	12.09 ± 1.09a	66.00 ± 7.44a	1.38 ± 0.09a
HL-Fluvastatin treated rats	Mean ± SD	65.20 ± 5.40a	55.00 ± 4.13c	1099.91 ± 10.00a	−16.07	−13.52	−9.33	−26.59
	% change to C	+7.62	+35.90	+9.95	−39.86	39.52	+33.60	+46.03
	% change to HL	−34.20	−29.40	−41.77	55.63	56.51	22.81	23.14
	%improvement	55.96	56.60	78.89	6.89 ± 0.94c	12.86 ± 1.09a	66.33 ± 10.28a	1.495 ± 0.08a

TC: Total cholesterol, TG: Total triglyceride, TL: Total lipids. MDA: Malondialdehyde, NO: Nitric Oxide, GSH: Glutathione reduced, TAC: Total antioxidant capacity. Data represented as mean ± SD of ten rats in each group. Statistical analysis is carried out using SPSS computer program, (one way analysis of variance), coupled with co-state computer program. Superscript unshared letters are significant at P < .05, where similar letters are considered insignificant at P > .05. These are statisctical results.