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. 2018 Aug 21;9:1938. doi: 10.3389/fmicb.2018.01938

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Copyright © 2018 Huang, Ding, Shi, Zhao, Hu, Ren, Huang, Wu and Zhao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparative analysis of the bla_KPC-harboring untypeable plasmids pFOS18 (KJ653815), pEC86 (MH328007), pKPC-ECN49 (KP726894), pHS062105-3 (KF623109), pP10159-3 (MF072963), pCP40 (MH328006), and pCKPC18-1 (CP022276). Light-blue shading denotes shared regions of homology in each adjacent plasmid. Notably, the type IV secretory pathway (VirB1-10) present in pKPC-ECN49, pHS062105-3, pP10159-3, pCP40, and pCKPC18-1 is absent in pFOS18 and pEC86. Open reading frames (ORFs) are depicted by arrows and are colored based on predicted gene function. Resistance genes are indicated with deep-blue arrows.