Table 2.
Mutagenic efficiencies observed in injected F0 embryos and F1 founder screens.
| Injected screen results | Founder screen results | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Genes targeted | Injections (gene # targeted) | Mutated genes assayed | Target amplicons (%) | Target genes assayed | Mutated genes (%) | Potential founders screened | Founders identified (%) | Mutated amplicons (%) | Mutated genes (%) | |
| RP-linked targets | 8 | 7 (8) | 14 | 12 (86%) | 8 | 7 (88%) | 34 | 22 (65%) | 14 (100%) | 8 (100%) |
| Regeneration targets | 312 | 50 (150) | 120 | 95 (79%) | 91 | 84 (92%) | 41 | 26 (63%) | 27 (75%) | 20 (83%) |