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Reaction catalyzed by EptA. EptA is an esterase that cleaves PEA from phosphatidylethanolamine to release di-acylglycerol. The PEA remains transiently attached to the active site Thr280 residue before being transferred to the lipid A head group. PEA has only been transferred to the 1 position of lipid A in this figure however the 4′ position can also accommodate a PEA moiety.
