Table 6.

Adjusted odds ratios of HU among participants associated with vitamin B12 intake.

		Vitamin B12 Intake (mcg/day)					p for Trend
		Q1 (≤2.27) (n = 2552 )	Q2 (2.28–3.79) (n = 2560 )	Q3 (3.80–5.58) (n = 2547 )	Q4 (5.59–8.43) (n = 2549 )	Q5 (≥8.44) (n = 2549 )
Male (n = 12,757)	Model 1 Model 2 Model 5	Reference Reference Reference	0.98 (0.86, 1.11) 0.96 (0.84, 1.10) 0.95 (0.82, 1.09)	0.94 (0.82, 1.07) 0.93 (0.81, 1.06) 0.94 (0.81, 1.09)	0.79 (0.69, 0.91) 0.77 (0.67, 0.88) 0.79 (0.67, 0.93)	0.73 (0.64, 0.84) 0.72 (0.63, 0.83) 0.77 (0.64, 0.93)	<0.0001 <0.0001 0.0013
		Q1 (≤1.56) (n = 2450 )	Q2 (1.57–2.64) (n = 2446 )	Q3 (2.65–3.91) (n = 2443 )	Q4 (3.92–5.93) (n = 2441 )	Q5 (≥5.94) (n = 2438 )
Female (n = 12,218)	Model 1 Model 2 Model 5	Reference Reference Reference	0.89 (0.76, 1.04) 0.90 (0.77, 1.05) 0.89 (0.75, 1.04)	0.94 (0.81, 1.09) 0.94 (0.81, 1.10) 0.93 (0.79, 1.11)	0.82 (0.70, 0.96) 0.84 (0.71, 0.98) 0.85 (0.71, 1.02)	0.76 (0.65, 0.90) 0.78 (0.66, 0.91) 0.83 (0.67, 1.03)	0.0007 0.0019 0.1030

Model 1 adjusted for age, race/ethnicity; Model 2 adjusted for age, race/ethnicity, smoking status, drinking status, education background, marital status, hypertension status, and diabetes status; Model 5 adjusted for age, race/ethnicity, smoking status, drinking status, education background, marital status, hypertension status, and diabetes status, energy intake, protein intake, carbohydrate intake, vitamin E intake, folate intake, vitamin B6 intake, saturated fatty acids intake, monounsaturated fatty acids intake, polyunsaturated fatty acids intake, caffeine intake, STC, glucose, BMI, and STG.