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Inhibitory activities of PA and INH against TBNAT.
| Compounds | Inhibition (%) | IC50 (µM) |
|---|---|---|
| PA | 77.4 ± 0.33 | 8.7 ± 1.44 |
| INH | 96.3 ± 1.3 | 6.2 ± 1.22 |
IC50: half maximal inhibitory concentration; PA: psoromic acid; INH, isoniazid; TBNAT: M. tuberculosis arylamine-N-acetyltransferase. The results are presented as the mean ± S.D. of triplicate measurements.
