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. 2017 Nov 30;14(5):962–970. doi: 10.5114/aoms.2017.71855

Table V.

Attainment of LDL-C therapeutic goals depending on the CV risk and ≥ 50% reduction in LDL-C concentration among subpopulations treated with statin monotherapy or in combination with ezetimibe according to statin dose

Type of therapy regimen Dose of statins Attainment of LDL-C < 1.8 mmol/l N (%)* Attainment of LDL-C < 2.6 mmol/l N (%)* Attainment of therapeutic goal: ≥ 50% reduction in LDL-C N (%)*
Very high CV risk High CV risk Very high CV risk High CV risk
Statin monotherapy 4 (28.6) 29 (37.7) 8 (57.1) 44 (57.1)
Statin monotherapy High 3 (27.3) 11 (39.3) 6 (54.5) 18 (64.3)
Moderate 1 (33.3) 17 (37.8) 2 (66.7) 25 (55.6)
Low 0 (0) 1 (25.0) 0 (0) 1 (25.0)
Statin in combination with ezetimibe 1 (3.8) 17 (23.3) 18 (69.2) 43 (58.9)
Statin in combination with ezetimibe High 1 (5.3) 10 (19.2) 14 (73.7) 33 (63.5)
Moderate 0 (0) 6 (30.0) 4 (57.1) 9 (45.0)
Low 0 (0) 1 (100.0) 0 (0) 1 (100.0)
*

The percentages in parentheses represent the prevalence of patients with target levels of LDL-C in CV risk subpopulations on particular therapy regimens.