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Restoration of STAT3 expression in fetal ASM cells. Cells were co-transfected with pcDNA3.1/STAT3 vector and miR-590-5p mimics for 48 h and then treated with PDGF (25 ng/ml) for 24 h. A – Protein expression of STAT3 was detected by Western blot. mRNA expression of cyclin D3 (B) and p27 (C) was detected by RT-qPCR
*p < 0.05 vs. NC + vector. &p < 0.05 vs. miR-590-5p mimics + vector.
