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Restoration of STAT3 reversed the inhibitory effect of miR-590-5p on ASM cell proliferation. Cells were co-transfected with pcDNA3.1/STAT3 vector and miR-590-5p mimics for 48 h and then treated with PDGF (25 ng/ml) for 24 h. A – Cell growth and viability were detected by CCK-8 assay. B – Cell proliferation was measured by BrdU assay
*p < 0.05 vs. NC + vector. &p < 0.05 vs. miR-590-5p mimics + vector.
