Table 3.

Summary of diagnostic statistics after the analysis of 30 patients by two radiologists using the MRI algorithm. Sensitivity = TP/(TP + FN); Specificity = TN/(TN + FP); PPV = TP/(TP + FP); NPV = TN/(TN + FP). Point estimates are followed by 95% confidence intervals in brackets.

	Sensitivity	Specificity	PPV	NPV
Radiologist 1	100 (–)	50.0 (19.0–81.0)	80.0 (64.3–95.7)	100 (–)
Radiologist 2	100 (–)	10.0 (-8.59–28.6)	69.0 (52.1–85.8)	100 (–)
MEAN	100 (–)	30.0 (1.60–58.4)	74.1 (57.5–90.6)	100 (–)

Twenty patients were diagnosed with a specific WMA and 10 were given non-specific diagnoses (etiology unknown). Prevalence of a specific diagnosed condition was 66.7%. Values shown include true positive (TP), true negative (TN), false positive (FP) and false negative (FN). Outcomes are presented by individual radiologist and as combined totals.

MRI: magnetic resonance imaging; NPV: negative predictive value; PPV: positive predictive value; WMA: white matter abnormality.