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. 2018 Aug 3;40(4):2047–2055. doi: 10.3892/or.2018.6626

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Copyright: © Zhu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — Scratch analysis showing the rate of cell migration of the HCC-1937, MX-1 and MCF-7 cell lines when ILP-2 was separately knocked down for 24, 48 and 72 h. (A) In regards to the HCC-1937 cell line, the rate of cell migration of the siRNA-5 group was notably decreased compared to the HCC-1937 group. *P<0.05, **P<0.01, ***P<0.001 vs. the HCC-1937 group, ^##P<0.01, ^###P<0.001 vs. the NC group. (B) In regards to the MX-1 cell line, the rate of cell migration of the siRNA-5 group was notably decreased compared to the MX-1 group. *P<0.05, **P<0.01, ***P<0.001 vs. the MX-1 group; ^##P<0.01 vs. the NC group; ^$P<0.05 vs. the siRNA-3 group. (C) In regards to the MCF-7 cell line, the rate of cell migration of the siRNA-5 group was notably decreased compared to the MCF-7 group. *P<0.05, **P<0.01, ***P<0.001 vs. the MCF-7 group. Data are expressed as mean ± SEM by ANOVA. Groups were compared by conducting Bonferroni test. Scale bar, 200 µm; n=3.

Figure 6. — Scratch analysis showing the rate of cell migration of the HCC-1937, MX-1 and MCF-7 cell lines when ILP-2 was separately knocked down for 24, 48 and 72 h. (A) In regards to the HCC-1937 cell line, the rate of cell migration of the siRNA-5 group was notably decreased compared to the HCC-1937 group. *P<0.05, **P<0.01, ***P<0.001 vs. the HCC-1937 group, ^##P<0.01, ^###P<0.001 vs. the NC group. (B) In regards to the MX-1 cell line, the rate of cell migration of the siRNA-5 group was notably decreased compared to the MX-1 group. *P<0.05, **P<0.01, ***P<0.001 vs. the MX-1 group; ^##P<0.01 vs. the NC group; ^$P<0.05 vs. the siRNA-3 group. (C) In regards to the MCF-7 cell line, the rate of cell migration of the siRNA-5 group was notably decreased compared to the MCF-7 group. *P<0.05, **P<0.01, ***P<0.001 vs. the MCF-7 group. Data are expressed as mean ± SEM by ANOVA. Groups were compared by conducting Bonferroni test. Scale bar, 200 µm; n=3.