Table III.

Pathway enrichment analysis based on coexpressing genes of GSDMD from expression Ombibus (GEO) array.

Pathway	Out (119)	All (8,248)	P-value	Q-value
Rap1 signaling pathway	8	157	0.001895346	0.05907162
ErbB signaling pathway	5	67	0.002720708	0.06275739
Hippo signaling pathway	4	52	0.006542435	0.10558077
PI3K-Akt signaling pathway	9	240	0.007739042	0.10558077
Phospholipase D signaling pathway	5	100	0.01458475	0.15151935
MAPK signaling pathway	7	190	0.01981771	0.15933242
Hippo signaling pathway	5	109	0.02044908	0.15933242
Ras signaling pathway	6	167	0.03352433	0.20583959
TGF-β signaling pathway	3	67	0.07217501	0.2871644
NF-κB signaling pathway	3	90	0.1404493	0.39659881
Calcium signaling pathway	4	141	0.1462627	0.40222242
Wnt signaling pathway	3	103	0.1858804	0.4634618
MAPK signaling pathway	1	17	0.2190935	0.51861373
Jak-STAT signaling pathway	3	130	0.2891426	0.60752434
HIF-1 signaling pathway	2	76	0.3000821	0.62350392
AMPK signaling pathway	2	84	0.3425983	0.66347952
cAMP signaling pathway	3	147	0.3564909	0.66347952
FoxO signaling pathway	2	100	0.4248353	0.72222001
VEGF signaling pathway	1	39	0.4333989	0.73014049
Sphingolipid signaling pathway	1	78	0.6798369	0.80974204
TNF signaling pathway	1	90	0.7315566	0.81262773
cGMP-PKG signaling pathway	1	118	0.8222264	0.86379964